Systematic research synthesis requires researchers to search for and identify a large body of studies that may be relevant to a review (see the Databases page in this site for links to reference searching facilities). Reviewers will then need to download references for these studies into some references manager software such as EndNote or Reference Manager. Once the references have been downloaded they will need to be screened for relevance to the review. Lastly these studies will go through a process of being coded and assessed. Managing all this information is often a very difficult task. The EPPI-Centre has developed some tools for assisting reviewers to manage this process